A manuscript on which Shaun collaborated with Garam (Celine) Han and other members of Frank Pugh’s and Ross Hardison’s labs has been published. “Genome-wide organization of Gata1 and Tal1 determined at high resolution” appears in Molecular and Cell Biology. In the paper, Garam has used ChIP-exo to determine the positional organization of Gata1 and Tal1 across the mouse genome during erythroid development. Careful analysis of the ChIP-exo crosslinking patterns reflect positional arrangement within a complex. Garam shows that TAL1 and GATA1 form a precisely organized complex at a compound motif consisting of a TG 7 or 8 bp upstream of a WGATAA motif across thousands of genomic locations.
